Semaglutide for Weight Loss in Long Island, New York
Including semaglutide and GLP-1 based treatment plans
Physician-guided semaglutide care with clear dosing, real follow-up, and local support from a licensed medical team serving Nassau and Suffolk County. Options may include compounded semaglutide, branded Wegovy, or high-dose Wegovy HD when clinically appropriate. Programs start at $149/month. Prefer a different approach? We also offer tirzepatide treatment and an oral GLP-1 pill option.
- Physician-guided care
- Long Island, NY based
- Telehealth follow-up available
In-office care with telehealth follow-up available · Nassau & Suffolk County
- Physician-prescribed & monitored
- Compounded from $179/month
- Wegovy HD (7.2 mg) now available
- Telehealth & in-office options
- Insurance assistance provided
20.7%
avg. body weight lost on high-dose 7.2mg (STEP UP trial, 72 weeks)
$149
starting monthly price for compounded semaglutide
1×
weekly injection — simple, low-friction routine
What Is Semaglutide
A Clinically Studied GLP-1 Option for Medical Weight Loss
Semaglutide is a GLP-1 receptor agonist — a medication that mimics a natural hormone your body releases after eating. It targets appetite-regulating centers in the brain, slows gastric emptying, and may help support blood sugar regulation, making it easier to reduce intake and lose weight consistently over time.
FDA-approved for chronic weight management as Wegovy (injection), with a new high-dose Wegovy HD at 7.2 mg approved in March 2026. At StackMD, we prescribe compounded, branded, and high-dose options — all under direct physician oversight from our Long Island, NY clinic. Need a stronger approach? Some patients may be better candidates for tirzepatide treatment.
How Semaglutide Works
Appetite Regulation
Signals the brain's hunger centers to help reduce appetite and cravings, designed to improve portion control over time.
Slowed Gastric Emptying
Food moves more slowly through your digestive system, extending fullness after meals.
Blood Sugar Support
Stimulates insulin release in response to food, helping support blood glucose regulation — especially helpful for insulin resistance.
Physician-Guided Titration
Dose is started low and increased gradually to minimize side effects while optimizing results.
FDA Approved · March 2026 New High-Dose Option
Wegovy HD — Semaglutide 7.2 mg
For patients who have tolerated the standard 2.4 mg Wegovy dose and need stronger results, the FDA approved Wegovy HD — a 7.2 mg weekly semaglutide injection — in March 2026. It is indicated for adults with obesity who have tolerated the 2.4 mg dose for at least 4 weeks and require additional weight reduction.
In the STEP UP Phase 3b trial published in The Lancet Diabetes & Endocrinology, patients on the 7.2 mg dose achieved an average weight loss of 20.7% over 72 weeks — compared to 17.5% at the standard 2.4 mg dose. Approximately one in three patients lost 25% or more of their body weight. Ask about eligibility at your consultation.
20.7%
average weight loss at 7.2 mg over 72 weeks
~1 in 3
patients achieved 25%+ body weight reduction
+3.2%
greater weight loss vs. standard 2.4 mg dose
Compare Options
Semaglutide vs. Tirzepatide: Which Is Right for You?
Both are physician-prescribed GLP-1 class medications available at StackMD in Long Island, NY. Here’s a clear way to think about the difference before your consultation.
Compare Options
Semaglutide
The most widely studied GLP-1 medication for weight loss. Weekly injection with a strong, well-established safety profile. Available as compounded, branded Wegovy, or the new high-dose Wegovy HD (7.2 mg). May help support 15–20%+ body weight reduction. A strong starting point for most patients new to GLP-1 therapy — and now available in a daily oral pill through our oral GLP-1 program.
You’re already here ✓
Higher Potency Option
Tirzepatide
A dual-action medication targeting both GLP-1 and GIP receptors simultaneously. In the SURMOUNT-5 head-to-head trial (NEJM, 2025), tirzepatide produced nearly 50% greater weight loss than semaglutide. May be a better fit for patients with insulin resistance, prior GLP-1 use, or those looking to maximize clinical outcomes.
Your physician will review your labs, history, and goals to help guide the best option for you. Schedule a consultation →
Your Program at StackMD
How the Program Works
Every step of your semaglutide program is guided by your StackMD physician — in Nassau County, Suffolk County, or anywhere on Long Island, NY.
Initial Consultation
Your physician reviews your full medical history, symptoms, goals, and weight-related health conditions to confirm candidacy and identify the right protocol via telehealth or in-office.
Lab Work & Assessment
Advanced metabolic labs evaluate blood sugar, hormones, inflammation, and nutrient status. Results help determine whether semaglutide or tirzepatide is the better fit for your metabolic picture.
Prescription & Protocol
You receive your individualized semaglutide prescription shipped to you with clear injection instructions, dosing schedule, and dietary guidance from our clinical team.
Ongoing Monitoring
Regular follow-ups allow your physician to track progress, review lab trends, and adjust your dose whether you're on compounded semaglutide, branded Wegovy, or Wegovy HD.
The process is simple. The guidance is real.
Most patients are seen within a few days. Your program begins after a thorough physician evaluation — not a rushed intake form.
Program Pricing
Compare Your Semaglutide Options
$149/mo
starting price per month
Physician-guided compounded semaglutide with flexible titration and dosing based on clinical response. Most affordable entry point.
$299/mo
starting price per month
Cash-pay access to branded semaglutide through Novo Nordisk programs when insurance is not used.
$25/mo
based off copay and insurance coverage
Branded semaglutide (Wegovy) through insurance. Coverage varies by plan. Please contact your insurance first.
Questions about cost? We'll walk you through it.
Compounded semaglutide starts at $149/month. We help with insurance verification for branded Wegovy and can help you find the right fit for your budget.
Frequently Asked Questions
Questions Patients Ask About Semaglutide
How much weight can I lose on semaglutide?
Clinical trials show average weight loss of 15–17.5% of body weight with standard-dose semaglutide over approximately 68–72 weeks. Patients on the newer high-dose 7.2 mg formulation achieved an average of 20.7% in the STEP UP trial. Individual results may vary based on starting weight, dose, adherence, and lifestyle factors.
What's the difference between semaglutide and tirzepatide?
Is semaglutide available in Long Island, NY — Nassau County and Suffolk County?
Yes. StackMD is a Long Island, NY-based medical practice serving patients across Nassau County, Suffolk County, and surrounding New York areas. We offer both in-office appointments and telehealth follow-up, so patients throughout Long Island, NY can access physician-supervised semaglutide weight loss care without disrupting their schedule.
Do I need labs before starting semaglutide?
Baseline labs are strongly recommended and help your physician tailor your program. A metabolic panel covering blood sugar, hormones, inflammation markers, and lipids helps determine your candidacy, guides medication selection (semaglutide vs. tirzepatide), and provides a baseline to track your progress. StackMD can coordinate lab work as part of your initial evaluation.
How is semaglutide administered?
Semaglutide for weight loss is given as a once-weekly subcutaneous injection, typically in the abdomen, thigh, or upper arm. Your StackMD physician will review proper injection technique and rotation sites at your first visit. A needle-free oral option is also available — learn more about our oral GLP-1 program.
What is the difference between Ozempic and Wegovy?
Both contain semaglutide, but they are FDA-approved for different indications. Ozempic (0.5–2 mg) is approved for type 2 diabetes. Wegovy (2.4 mg) is approved specifically for chronic weight management. Wegovy HD (7.2 mg) is the newest high-dose option for weight loss, approved in March 2026.
What is compounded semaglutide?
Compounded semaglutide is prepared by licensed 503B outsourcing facilities or state-licensed compounding pharmacies. It contains the same active molecule as branded semaglutide and is significantly more affordable. StackMD works exclusively with high-quality, licensed compounding partners.
Is semaglutide covered by insurance?
Coverage depends on your specific plan. Branded Wegovy may be covered with prior authorization. StackMD assists with benefit verification and prior authorization support. Compounded semaglutide is typically not covered by insurance but is available at a significantly lower out-of-pocket cost starting at $179/month.
Patient Experiences
Real patients. Real results.
“I was nervous to start but the process was so smooth. Within two months I’d lost 18 pounds. Having a real doctor check in every few weeks made me feel like I wasn’t just winging it — someone was actually watching out for me.”
Rachel T. — Nassau County
“The compounded semaglutide option made this actually affordable for me. $179 a month and I’m down 21 pounds over five months. The telehealth visits are quick and the doctor always knows exactly where I am in the protocol.”
James K. — Suffolk County
“I appreciated that they actually ran labs before putting me on anything. It felt like real medical care, not just a subscription box. Down 24 pounds and my blood sugar numbers have improved significantly too.”
Maria S. — Long Island, NY
Explore More Options
Other Weight Loss Programs at StackMD
Injectable · Dual Hormone
Tirzepatide (Zepbound)
One of the highest-efficacy injectables available. Dual GLP-1 & GIP action for superior weight loss outcomes. Starting at $199/month.
Oral · No Injections
Oral GLP-1 (Wegovy Pill)
FDA-approved December 2025. Needle-free, physician-guided oral GLP-1 care for patients who want a simpler daily option with real clinical oversight and structured follow-up.
All Options
Medical Weight Loss Program
Not sure which medication is right for you? View our full weight loss program overview and compare all available options.
Ready to Begin Your Semaglutide Program?
StackMD serves patients across Long Island, NY, Nassau County, Suffolk County, and surrounding New York areas. In-office and telehealth appointments available.